Vancomycin minangka antibiotik glikopeptida sing digunakake kanggo antibakteri
Detail Produk
| jeneng | Vankomisin |
| Nomer CAS | 1404-90-6 |
| Rumus molekul | C66H75Cl2N9O24 |
| Bobot molekul | 1449.25 |
| Nomer EINECS | 215-772-6 |
| Kapadhetan | 1.2882 (kira-kira kasar) |
| Indeks bias | 1.7350 (takiran) |
| Kondisi panyimpenan | Ditutup ing garing, 2-8 ° C |
sinonim
Vankomisin(basa lan/orunspecifiedsalts);VANCOMYCIN;VancomycinBase;(3S,6R,7R,22R,23S,26S,36R,38aR)-3-(2-Amino-2-oxoethyl)-44-[[2-O-( 3-amino-2,3,6-trideoxy-3-C-methyl-α-L-lyxo-hexopyranosyl)-β-D-glucopyranosyl]oxy]-10,19-dichloro-2,3,4,5, 6,7,23,24,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-[[(2R)-4-methChemicalbookyl-2-(methylamino )-1-oxopentyl]amino]-2,5,24,38,39-pentaoxo-22H-8,11:18,21-Dietheno-23,36-(iminomethano)-13,16:31,35-dimetheno -1H,16H-[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylicacid.
Katrangan
Vancomycin minangka antibiotik glikopeptida.Mekanisme tumindake yaiku kanggo ngiket kanthi afinitas dhuwur menyang alanylalanine ing ujung poli-terminal saka peptida prekursor saka tembok sel bakteri sing sensitif, ngalangi sintesis peptidoglikan makromolekul sing mbentuk tembok sel bakteri, sing nyebabake karusakan sel. tembok mateni bakteri.Vancomycin efektif kanggo infeksi serius sing disebabake dening bakteri Gram-positif, utamane sing disebabake dening Staphylococcus aureus sing tahan methicillin, Staphylococcus epidermidis, lan Enterococcus sing tahan kanggo antibiotik liya utawa nduweni khasiat sing kurang.
indikasi
Iki diwatesi kanggo infeksi sistemik sing disebabake dening Staphylococcus aureus (MRSA) sing tahan methicillin lan infeksi usus lan infeksi sistemik sing disebabake dening Clostridium difficile;Pasien alergi penisilin ora bisa nggunakake penisilin utawa cephalosporin ing pasien sing kena infeksi staphylococcal abot, utawa sing duwe infeksi staphylococcal abot sing ora nanggapi antibiotik ing ndhuwur, vankomisin bisa digunakake.Produk iki uga digunakake kanggo perawatan endokarditis Enterococcus lan endokarditis Corynebacterium (kaya Diphtheria) ing wong sing alergi marang penisilin.Perawatan infeksi shunt arteriovenous sing disebabake staphylococcus ing pasien hemodialisis alergi penisilin lan non-alergi kanggo penisilin.
