Jeneng | Ru-58841 |
Nomer CAS | 154992-2-2 |
Formula Molekuler | C17h18f3n3o3 |
Bobot molekuler | 369.34 |
Nomer EineCECT | 1592732-453-0 |
Titik Giling | 493.6 ± 55.0 ° C (diprediksi) |
Kapadhetan | 1.39 |
Kondisi panyimpenan | Disegel ing garing, simpen ing freezer, ing under -20 ° C |
Formulir | Wêdakakêna |
Werna | Putih |
Paket | PE TAGE + BAG ALUMINUM |
Ru58841; 4- (4,4-dimethyl-2,5-dioxo-3- (4-hydroxybutyl) 1-iDidaolidinyl) -2- (TrifLuoromethyl) Benzo nitrile; 4- [3- (4-hydroxybutyl) -4,4-dimethtyl-1,5-dioxo-1-imidazolidinyl] -2- (trifluoromethyl) benz onitrile; 4- [3- (4-hydroxybutyl) -4,4-dimoxyl-2,5-dixoimyazolidin-1-yl] -2- (trifluoromethyl) ben Zonitrile; Ru-58841E: Candyli (ing) SpeedGainpharma (Dot) Com; CS-637; RU588841; RU58841; Ru58841
Katrangan
Ru 58841 (PSK-3841) yaiku antagonis reseptor androgen sing nyedhiyakake regrowth rambut.Ru58841 minangka obat investigasi sing digawe kanggo perawatan marang alopecia Androgenik, uga dikenal minangka pola botak lanang (MPD).
Minangka anti-androgen topikal, prinsip tumindak ora padha karo finasteride. FINASTERTAIDE langsung tumindak ing 5α redsectase, nyegah konversi testosteron menyang DHT, lan nyuda isi DHT ing awak. Ru58841 ngalangi kontak ing antarane reseptor dihydrotestosteron lan rambut, nanging ora bisa nyuda konten DHT, nanging nyuda naleni reseptor DHT lan recets folikel rambut, supaya bisa nambani alopecia lan rambut rambut.
4- [3- (4-Hydroxybutyl) -4,4-dimethyl-1,5-dioxolidinyl] -2- (Trifluoromethyl) Benzonitrile bisa digunakake minangka obat sintesis kimia.Yen 4- [3- (4-hydroxybutyl) -4,4-dimoxyl-1,5-dioxolidinyl] -2- ((Trifluoromethyl) Benzonitrile dialami, mindhah pasien udhara seger;Ing kasus kontak kulit, mbusak sandhangan sing kontaminasi, cuci kulit kanthi sinetron kanthi sinetron lan banyu, lan golek perhatian medis yen rasa ora kepenak;
Efek sisih
Ru58841 ditrapake ing kulit kepala, diserep dening folikel rambut, lan kanthi teoritis, bisa mlebu ing aliran getih lan mengaruhi bagean awak liyane. Nanging ora ana efek samping sistemik ing pasinaon aplikasi topikal ing monyet. Nanging, sawetara wong sing nyoba Ru588841 pratelan dheweke wis ngalami sawetara efek samping saka nggunakake ru, kalebu libido kulit, kalebu libido kulit, mual, mata abang, pusing, lan sirah.