RU-58841 Digunakake minangka Nyegah Rambut Rontok lan Botak Pola Lanang
Detail Produk
| jeneng | RU-58841 |
| Nomer CAS | 154992-24-2 |
| Rumus molekul | C17H18F3N3O3 |
| Bobot molekul | 369.34 |
| Nomer EINECS | 1592732-453-0 |
| Titik didih | 493.6±55.0 °C(Prediksi) |
| Kapadhetan | 1.39 |
| Kondisi panyimpenan | Disegel ing garing, Simpen ing freezer, ing -20 ° C |
| Wangun | wêdakakêna |
| warna | Putih |
| Packing | Tas PE + tas Aluminium |
sinonim
RU58841;4-(4,4-Dimetil-2,5-dioxo-3-(4-hydroxybutyl)1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile;4-[3-(4-Hydroxybutyl)-4,4-dimetil-2,5-dioxo-1-imidazolidinyl-1-imidazolidi onitril;4-[3-(4-Hydroxybutyl)-4,4-diMethyl-2,5-dioxoiMidazolidin-1-yl]-2-(trifluoroMethyl)ben zonitrile;RU-58841E:candyli(ing)speedgainpharma(dot)com;CS-637;RU588841;RU58841;RU58841;RU-58841
Efek Farmakologis
Katrangan
RU 58841 (PSK-3841) minangka antagonis reseptor androgen sing ningkatake pertumbuhan rambut maneh.RU58841 minangka obat investigasi sing digawe kanggo perawatan nglawan alopecia androgenik, uga dikenal minangka botak pola lanang (MPD).
Minangka anti-androgen topikal, prinsip tumindake ora padha karo finasteride. Finasteride langsung tumindak ing 5α reduktase, nyegah konversi testosteron dadi DHT, lan nyuda isi DHT ing awak. RU58841 mblokir kontak antarane reseptor dihydrotestosteron lan folikel rambut, ora langsung nyuda isi DHT, nanging nyuda ikatan DHT lan reseptor folikel rambut, supaya bisa nggayuh tujuan ngobati alopecia androgenetik.
4-[3-(4-Hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl]-2-(trifluoromethyl)benzonitrile bisa digunakake minangka obat Perantara sintesis kimia.Yen 4-[3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl]-2-(trifluoromethyl)benzonitrile dihirup, Pindhah pasien menyang hawa seger;Yen kena kulit, copot sandhangan sing kena kontaminasi, mbilas kulit kanthi sabun lan banyu, lan golek bantuan medis yen ana rasa ora nyaman;
Efek sisih
RU58841 ditrapake ing kulit sirah, diserap dening folikel rambut, lan kanthi teoritis, bisa mlebu aliran getih lan mengaruhi bagean awak liyane. Nanging ora ana efek samping sistemik sing ditemokake ing studi babagan aplikasi topikal ing kethek. Nanging, sawetara wong sing wis nyoba RU58841 ngaku wis ngalami sawetara efek samping saka nggunakake RU, kalebu iritasi kulit, nyuda libido, disfungsi ereksi, mual, mata abang, pusing, lan sirah.
