Jeneng | Eptifibatide |
Nomer CAS | 188627-80-77 |
Formula Molekuler | C35h49n11o9s2 |
Bobot molekuler | 831.96 |
Nomer EineCECT | 641-366-7 |
Kapadhetan | 1,60 ± 0,1 g / cm3 (diprediksi) |
Kahanan panyimpenan | Disegel ing garing, simpen ing freezer, under -15 ° C |
Epifibatideacetatest; eptifibatide, mpa-har-ASP-trp-pro-asp,> 99%; eptifibatide; eptifibatide; n6- (aminoimi nomethyl) -N2- (3-mercapto-1-oxopropyl-l-lysylglycyl-la-lysylglycyl-la-aspartyl-l-tryptophyl-l-tryptophyl-asp-trp-pro-ASP-CYS-CYS6).
Etifibatide (integrilin) minangka novel platelet glikoprotein iib / Antagonist reseptor iib / sing nyegah agregasi dandar platelet lan trombosis kanthi nyandhet jalur platelet pungkasan. Dibandhingake karo Antibody abciximab, eptifibatide duwe naleni sing luwih kuat lan luwih arah menyang GPiib / IIia amarga ana asile asam amino sing dibutuhake kanggo lysine kanggo ngganti arginine. Mula, kudu duwe efek terapi sing apik ing perawatan sindrom koroner akut. Plombing Glikoprotein IIB / iiia receptor Obat antagonis IIia wis dikembangake akeh, lan saiki ana 3 jinis persiyapan sing bisa digunakake ing klinis internasional, abciximab, eptifibatide lan tirofiban lan tirofiban. ). Ora ana pengalaman sing sithik ing panggunaan antagonis glikoprotein Glikoprotein Glikoprotein Glikoprotein Glikoprotein Glikoprotein Glikoprotein Glikoprotein Glikoprotein Glikoprotein Glikorets ing China, lan obat-obatan sing kasedhiya uga diwatesi. Mung siji obat, tirofiban hydrochloride, ana ing pasar. Mula, glycoprotein anyar glikoprotein iib dikembangake. / Antagonis reseptor IIia imperatif. Epticalize domestik minangka produk tiruan sing diasilake dening Chengdu Sino Biologi Produk Co, Ltd
Klasifikasi Obat Aggregasi Antiplatelet
Obat-obatan agregasi Antiplatetelet bisa dipérang dadi telung kategori: 1. Inhibitor-1 (COX-1) inhibitor, kayata aspirin. 2. Ngarsane tromboset mlebu dening adenosine diphosfate (ADP), kayata Clopidogrel, Prasugrel, Cangagonide, kayata Inhibitors, komponen kimia anyar lan ekstrak saka obat tradisional Cina.